Modulation of bacterial Type III secretion system by a spermidine transporter dependent signaling pathway.

BACKGROUND: Many gram-negative bacterial pathogens employ Type III secretion systems (T3SS) to inject effector proteins into host cells in infectious processes. METHODOLOGY/PRINCIPAL FINDINGS: By screening a transposon mutant library of P. aeruginosa, we found that mutation of spuDEFGH, which encode...

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Bibliographic Details
Main Authors: Lian Zhou, Jing Wang, Lian-Hui Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2110884?pdf=render