Formation of Polyploid Giant Cancer Cells Involves in the Prognostic Value of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer

We previously reported that polyploid giant cancer cells (PGCCs) exhibit cancer stem cell properties and can generate daughter cells with the epithelial-mesenchymal transition phenotype. This study investigated the role of PGCC formation in the prognostic value of neoadjuvant chemoradiation therapy...

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Bibliographic Details
Main Authors: Fei Fei, Mingqing Zhang, Bo Li, Lizhong Zhao, Hui Wang, Lina Liu, Yuwei Li, Po Ding, Yanjun Gu, Xipeng Zhang, Tao Jiang, Siwei Zhu, Shiwu Zhang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2019/2316436