MTL-CEBPA Combined with Immunotherapy or RFA Enhances Immunological Anti-Tumor Response in Preclinical Models

MTL-CEBPA Combined with Immunotherapy or RFA Enhances Immunological Anti-Tumor Response in Preclinical Models

The transcription factor CEBPA is a master regulator of liver homeostasis, myeloid cell differentiation and is downregulated in several oncogenic diseases. MTL-CEBPA is a small activating RNA drug which upregulates gene expression of CEBPA for treatment of hepatocellular carcinoma (HCC). We investig...

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Bibliographic Details
Main Authors: Kai-Wen Huang, Choon Ping Tan, Vikash Reebye, Cheng Ean Chee, Dimitris Zacharoulis, Robert Habib, David C. Blakey, John J. Rossi, Nagy Habib, Mikael H. Sodergren
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
CEBPA
abscopal
immunotherapy
PD-1
Online Access:https://www.mdpi.com/1422-0067/22/17/9168

Internet

https://www.mdpi.com/1422-0067/22/17/9168

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