P2Y2 receptor knock-out mice display normal NaCl absorption in medullary thick ascending limb

Local purinergic signals modulate renal tubular transport. Acute activation of renal epithelial P2 receptors causes inhibition of epithelial transport and thus, should favor increased water and salt excretion by the kidney. So far only a few studies have addressed the effects of extracellular nucleo...

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Bibliographic Details
Main Authors: Rita Delgado Marques, Helle A. Praetorius, Jens eLeipziger
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00280/full