Suppression of hepatitis b virus by a combined activity of CRISPR/Cas9 and HBx proteins

Suppression of hepatitis b virus by a combined activity of CRISPR/Cas9 and HBx proteins

Chronic hepatitis B is a severe liver disease associated with persistent infection with hepatitis B virus. According to recent estimations, 250 million people in the world are chronically infected, including 3 million chronically infected people in Russia. Antiviral therapeutics (nucleos(t)ide analo...

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Bibliographic Details
Main Authors: S. A. Brezgin, A. P. Kostyusheva, V. N. Simirsky, E. V. Volchkova, D. S. Chistyakov, D. S. Kostyushev, V. P. Chulanov
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2019-11-01
Series:Infekciâ i Immunitet
Subjects:
hepatitis b virus
circular covalently closed dna
crispr/cas9
specificity
hbx protein
mutant forms of hbx protein
Online Access:https://www.iimmun.ru/iimm/article/view/922

Internet

https://www.iimmun.ru/iimm/article/view/922

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