The Bioequivalence of Emulsified Isoflurane With a New Formulation of Emulsion: A Single-Center, Single-Dose, Double-Blinded, Randomized, Two-Period Crossover Study

The Bioequivalence of Emulsified Isoflurane With a New Formulation of Emulsion: A Single-Center, Single-Dose, Double-Blinded, Randomized, Two-Period Crossover Study

Background: Emulsified isoflurane is a novel intravenous general anesthetic obtained by encapsulating isoflurane molecules into emulsion. The formulation of emulsion has been improved according to the latest regulations of the China Food and Drug Administration. This study was designed to compare th...

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Bibliographic Details
Main Authors: Hui Yang, Qinqin Yin, Luying Huang, Min Zhang, Xinxin Zhang, Qirong Sun, Xuewei Liu, Qi Wang, Xi Yang, Lingcan Tan, Mao Ye, Jin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
emulsified isoflurane
Cmax
AUC0-t
AUC0-∞
bioequivalence
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.626307/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.626307/full

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