Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria.

Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria.

BACKGROUND:The Plasmodium vivax Duffy Binding Protein (PvDBP) is a key target of naturally acquired immunity. However, region II of PvDBP, which contains the receptor-binding site, is highly polymorphic. The natural acquisition of antibodies to different variants of PvDBP region II (PvDBPII), includ...

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Bibliographic Details
Main Authors: Wen-Qiang He, Ahmad Rushdi Shakri, Rukmini Bhardwaj, Camila T França, Danielle I Stanisic, Julie Healer, Benson Kiniboro, Leanne J Robinson, Micheline Guillotte-Blisnick, Christèle Huon, Peter Siba, Alan Cowman, Christopher L King, Wai-Hong Tham, Chetan E Chitnis, Ivo Mueller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6400399?pdf=render

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http://europepmc.org/articles/PMC6400399?pdf=render

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