Myosin IIA deficient cells migrate efficiently despite reduced traction forces at cell periphery

Summary Cell motility is a cornerstone of embryogenesis, tissue remodeling and repair, and cancer cell invasion. It is generally thought that migrating cells grab and exert traction force onto the extracellular matrix in order to pull the cell body forward. While previous studies have shown that myo...

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Bibliographic Details
Main Authors: Melissa H. Jorrisch, Wenting Shih, Soichiro Yamada
Format: Article
Language:English
Published: The Company of Biologists 2013-02-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/4/368