Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in mice.

The Ste-20 family kinase Hippo restricts cell proliferation and promotes apoptosis for proper organ development in Drosophila. In C. elegans, Hippo homolog also regulates longevity. The mammalian Ste20-like protein kinase, Mst1, plays a role in apoptosis induced by various types of apoptotic stress....

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Bibliographic Details
Main Authors: Juhyun Choi, Sangphil Oh, Dongjun Lee, Hyun Jung Oh, Jik Young Park, Sean Bong Lee, Dae-Sik Lim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2776980?pdf=render