Revealing protein networks and gene-drug connectivity in cancer from direct information

Abstract The connection between genetic variation and drug response has long been explored to facilitate the optimization and personalization of cancer therapy. Crucial to the identification of drug response related genetic features is the ability to separate indirect correlations from direct correl...

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Bibliographic Details
Main Authors: Xian-Li Jiang, Emmanuel Martinez-Ledesma, Faruck Morcos
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04001-3