HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer

HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer

Abstract Background Colorectal cancer (CRC) is a common cancer worldwide. The main cause of death in CRC includes tumor progression and metastasis. At molecular level, these processes may be triggered by epithelial-mesenchymal transition (EMT) and necessitates specific alterations in cell metabolism...

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Main Authors: Elena A. Pudova, Anna V. Kudryavtseva, Maria S. Fedorova, Andrew R. Zaretsky, Dmitry S. Shcherbo, Elena N. Lukyanova, Anatoly Y. Popov, Asiya F. Sadritdinova, Ivan S. Abramov, Sergey L. Kharitonov, George S. Krasnov, Kseniya M. Klimina, Nadezhda V. Koroban, Nadezhda N. Volchenko, Kirill M. Nyushko, Nataliya V. Melnikova, Maria A. Chernichenko, Dmitry V. Sidorov, Boris Y. Alekseev, Marina V. Kiseleva, Andrey D. Kaprin, Alexey A. Dmitriev, Anastasiya V. Snezhkina
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Genomics
Subjects:
Warburg effect
Hexokinase
Glycolysis
Colorectal cancer
Epithelial-mesenchymal transition
Online Access:http://link.springer.com/article/10.1186/s12864-018-4477-4

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http://link.springer.com/article/10.1186/s12864-018-4477-4

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