Spatially coordinated dynamic gene transcription in living pituitary tissue

Spatially coordinated dynamic gene transcription in living pituitary tissue

Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene ex...

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Bibliographic Details
Main Authors: Karen Featherstone, Kirsty Hey, Hiroshi Momiji, Anne V McNamara, Amanda L Patist, Joanna Woodburn, David G Spiller, Helen C Christian, Alan S McNeilly, John J Mullins, Bärbel F Finkenstädt, David A Rand, Michael RH White, Julian RE Davis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-02-01
Series:eLife
Subjects:
Transcription Dynamics
Spatial Organisation
Stochastic Modelling
Live-Cell Microscopy
Pituitary
Online Access:https://elifesciences.org/articles/08494

Internet

https://elifesciences.org/articles/08494

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