The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia
Abstract Cystic fibrosis (CF) patients are extremely vulnerable to Burkholderia cepacia complex (Bcc) infections. However, the underlying etiology is poorly understood. We tested the hypothesis that short palate lung and nasal epithelial clone 1 (SPLUNC1)–epithelial sodium channel (ENaC) interaction...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12931-020-01454-5 |