The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia
Abstract Cystic fibrosis (CF) patients are extremely vulnerable to Burkholderia cepacia complex (Bcc) infections. However, the underlying etiology is poorly understood. We tested the hypothesis that short palate lung and nasal epithelial clone 1 (SPLUNC1)–epithelial sodium channel (ENaC) interaction...
Main Authors: | Saira Ahmad, Christine Seul Ki Kim, Robert Tarran |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2020-07-01
|
Series: | Respiratory Research |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12931-020-01454-5 |
Similar Items
-
Chitosan Nanocomplexes for the Delivery of ENaC Antisense Oligonucleotides to Airway Epithelial Cells
by: A. Katharina Kolonko, et al.
Published: (2020-04-01) -
Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity
by: Patrick J. Moore, et al.
Published: (2019-05-01) -
Chronic ß2AR stimulation limits CFTR activation in human airway epithelia
by: Brewington, John J., III
Published: (2021) -
Host evasion by Burkholderia cenocepacia
by: Shyamala eGanesan, et al.
Published: (2012-01-01) -
Effect of apical chloride concentration on the measurement of responses to CFTR modulation in airway epithelia cultured from nasal brushings
by: Preston E. Bratcher, et al.
Published: (2020-10-01)