Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.

Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.

The lipid lamellae in the stratum corneum is important for the epidermal permeability barrier. The lipid lamellae component ceramide (CER), comprising an ultra long-chain (ULC) fatty acid (FA) of ≥26 carbons (ULC CER), plays an essential role in barrier formation. ULC acyl-CoAs, produced by the FA e...

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Bibliographic Details
Main Authors: Yukiko Mizutani, Hui Sun, Yusuke Ohno, Takayuki Sassa, Takeshi Wakashima, Mari Obara, Kohei Yuyama, Akio Kihara, Yasuyuki Igarashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3694974?pdf=render

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http://europepmc.org/articles/PMC3694974?pdf=render

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