No Role of Osteocytic Osteolysis in the Development and Recovery of the Bone Phenotype Induced by Severe Secondary Hyperparathyroidism in Vitamin D Receptor Deficient Mice

No Role of Osteocytic Osteolysis in the Development and Recovery of the Bone Phenotype Induced by Severe Secondary Hyperparathyroidism in Vitamin D Receptor Deficient Mice

Osteocytic osteolysis/perilacunar remodeling is thought to contribute to the maintenance of mineral homeostasis. Here, we utilized a reversible, adult-onset model of secondary hyperparathyroidism to study femoral bone mineralization density distribution (BMDD) and osteocyte lacunae sections (OLS) ba...

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Bibliographic Details
Main Authors: Barbara M. Misof, Stéphane Blouin, Jochen G. Hofstaetter, Paul Roschger, Jochen Zwerina, Reinhold G. Erben
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin D receptor
mice with a non-functioning vitamin D receptor
bone mineralization density distribution
osteocyte lacunae sections
quantitative backscattered electron imaging
osteocytic osteolysis
Online Access:https://www.mdpi.com/1422-0067/21/21/7989

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https://www.mdpi.com/1422-0067/21/21/7989

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