κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance

κ-Opioid Signaling in the Lateral Hypothalamic Area Modulates Nicotine-Induced Negative Energy Balance

Several studies have reported that nicotine, the main bioactive component of tobacco, exerts a marked negative energy balance. Apart from its anorectic action, nicotine also modulates energy expenditure, by regulating brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning....

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Bibliographic Details
Main Authors: Patricia Seoane-Collazo, Amparo Romero-Picó, Eva Rial-Pensado, Laura Liñares-Pose, Ánxela Estévez-Salguero, Johan Fernø, Rubén Nogueiras, Carlos Diéguez, Miguel López
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
nicotine
kappa opioid receptor
lateral hypothalamus
AMPK
mTOR
Online Access:https://www.mdpi.com/1422-0067/22/4/1515

Internet

https://www.mdpi.com/1422-0067/22/4/1515

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