Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERα Inhibition

The anthraquinones emodin and aloe-emodin are abundant in rhubarb. Several lines of evidence indicate that emodin and aloe-emodin have estrogenic activity as phytoestrogens. However, their effects on estrogen receptor α (ERα) activation and breast cancer cell growth remain controversial. The goal of...

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Bibliographic Details
Main Authors: Pao-Hsuan Huang, Chih-Yang Huang, Mei-Chih Chen, Yueh-Tsung Lee, Chia-Herng Yue, Hsin-Yi Wang, Ho Lin
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2013/376123