Semaphorin SEMA3F and VEGF Have Opposing Effects on Cell Attachment and Spreading

Semaphorin SEMA3F and VEGF Have Opposing Effects on Cell Attachment and Spreading

SEMA3F, isolated from a 3p21.3 deletion, has antitumor activity in transfected cells, and protein expression correlates with tumor stage and histology. In primary tumors, SEMA3F and VEGF surface staining is inversely correlated. Coupled with SEMA3F at the leading edge of motile cells, we previously...

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Bibliographic Details
Main Authors: Patrick Nasarre, Bruno Constantin, Lydie Rouhaud, Thomas Harnois, Guy Raymond, Harry A. Drabkin, Nicolas Bourmeyster, Joëlle Roche
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
semaphorin SEMA3F
neuropilin
VEGF
cell spreading
small GTPases
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558603800209

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http://www.sciencedirect.com/science/article/pii/S1476558603800209

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