Leukemia-Initiating Cells in T-Cell Acute Lymphoblastic Leukemia

Leukemia-Initiating Cells in T-Cell Acute Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is a hematological malignancy characterized by the clonal proliferation of immature T-cell precursors. T-ALL has many similar pathophysiological features to acute myeloid leukemia, which has been extensively studied in the establishment of the cancer stem...

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Bibliographic Details
Main Authors: Shi Hao Tan, Fatima Carla Bertulfo, Takaomi Sanda
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Oncology
Subjects:
T-cell acute lymphoblastic leukemia
leukemia initiating cells
TAL1
NOTCH1
core regulatory circuit
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00218/full

Internet

http://journal.frontiersin.org/article/10.3389/fonc.2017.00218/full

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