When drug treatments bias genetic studies: Mediation and interaction.

<h4>Background</h4>Increasingly, genetic analyses are conducted using information from subjects with established disease, who often receive concomitant treatment. We determined when treatment may bias genetic associations with a quantitative trait.<h4>Methods</h4>Graph theory...

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Bibliographic Details
Main Authors: Amand F Schmidt, Hiddo J L Heerspink, Petra Denig, Chris Finan, Rolf H H Groenwold
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221209