Antagonizing programmed death-1 and programmed death ligand-1 as a therapeutic approach for gastric cancer

Malignant tumor cells are equipped with mechanisms that can help them escape the surveillance by host immune system. Immune checkpoint molecules can transduce coinhibitory signals to immunocompetent cells and exert immunosuppressive roles in antitumor immunity. Programmed death-1 (PD-1) and programm...

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Bibliographic Details
Main Authors: Xiaojun Liu, Zhongxia Yang, Olivier Latchoumanin, Liang Qiao
Format: Article
Language:English
Published: SAGE Publishing 2016-11-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756283X16658251