Transplantation of Encapsulated Hepatocytes during Acute Liver Failure Improves Survival without Stimulating Native Liver Regeneration

The aim of this study was to evaluate the effects of intraperitoneal transplantation of encapsulated human hepatocytes on liver metabolism and regeneration of mice with acute liver failure. Primary human hepatocytes were immortalized using lentiviral vectors coding for antiapoptotic genes and microe...

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Bibliographic Details
Main Authors: Antonino Sgroi, Gang Mai, Philippe Morel, Reto M. Baertschiger, Carmen Gonelle-Gispert, Véronique Serre-Beinier, Leo H. Buhler M.D.
Format: Article
Language:English
Published: SAGE Publishing 2011-12-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X564976