Contextual fear conditioning in virtual reality is affected by 5HTTLPR and NPSR1 polymorphisms: effects on fear-potentiated startle

Contextual fear conditioning in virtual reality is affected by 5HTTLPR and NPSR1 polymorphisms: effects on fear-potentiated startle

The serotonin (5-HT) and neuropeptide S (NPS) systems are discussed as important genetic modulators of fear and sustained anxiety contributing to the etiology of anxiety disorders. Sustained anxiety is a crucial characteristic of most anxiety disorders which likely develops through context condition...

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Bibliographic Details
Main Authors: Evelyn eGlotzbach-Schoon, Marta eAndreatta, Andreas eReif, Heike eEwald, Christian eTröger, Christian eBaumann, Jürgen eDeckert, Andreas eMühlberger, Paul ePauli
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
5HTTLPR
contextual fear conditioning
fear-potentiated startle
NPSR1
gene × gene interaction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00031/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00031/full

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