Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation

Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation

Abstract Age‐related macular degeneration (AMD) in its various forms is a leading cause of blindness in industrialized countries. Here, we provide evidence that ligands for neuropilin‐1 (NRP1), such as Semaphorin 3A and VEGF‐A, are elevated in the vitreous of patients with AMD at times of active cho...

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Bibliographic Details
Main Authors: Elisabeth M M A Andriessen, François Binet, Frédérik Fournier, Masayuki Hata, Agnieszka Dejda, Gaëlle Mawambo, Sergio Crespo‐Garcia, Frédérique Pilon, Manuel Buscarlet, Karine Beauchemin, Véronique Bougie, Garth Cumberlidge, Ariel M Wilson, Steve Bourgault, Flavio A Rezende, Normand Beaulieu, Jean‐Sébastien Delisle, Przemyslaw Sapieha
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:EMBO Molecular Medicine
Subjects:
age‐related macular degeneration
angiogenesis
inflammation
mononuclear phagocytes
neuropilin‐1
Online Access:https://doi.org/10.15252/emmm.201911754

Internet

https://doi.org/10.15252/emmm.201911754

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