Spatiotemporal Distribution of Agrin after Intrathecal Injection and Its Protective Role in Cerebral Ischemia/Reperfusion Injury

Spatiotemporal Distribution of Agrin after Intrathecal Injection and Its Protective Role in Cerebral Ischemia/Reperfusion Injury

Abstract Intrathecal injection, drugs transporting along perivascular spaces, represents an important route for maintaining blood–brain barrier (BBB) integrity after cerebral ischemia/reperfusion (I/R) injury. However, after being directly injected into cerebrospinal fluid (CSF), the temporal and sp...

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Bibliographic Details
Main Authors: Shiyong Li, Ye Wang, Dawei Jiang, Dalong Ni, Christopher J. Kutyreff, Todd E. Barnhart, Jonathan W. Engle, Weibo Cai
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Advanced Science
Subjects:
agrin
blood–brain barrier
ischemia/reperfusion injury
ischemic stroke
positron emission tomography
Online Access:https://doi.org/10.1002/advs.201902600

Internet

https://doi.org/10.1002/advs.201902600

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