Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity

Oxidative stress-associated endothelial dysfunction is a key pathogenic factor underlying the microvascular complications of metabolic disease. NADPH oxidase (Nox) is a major source of oxidative stress in diabetic nephropathy and chronic kidney disease, despite Nox4 and Nox2 have been identified as...

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Bibliographic Details
Main Authors: Mercedes Muñoz, Maria Elvira López-Oliva, Claudia Rodríguez, María Pilar Martínez, Javier Sáenz-Medina, Ana Sánchez, Belén Climent, Sara Benedito, Albino García-Sacristán, Luis Rivera, Medardo Hernández, Dolores Prieto
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719308031