Expanding metabolic engineering algorithms using feasible space and shadow price constraint modules
While numerous computational methods have been developed that use genome-scale models to propose mutants for the purpose of metabolic engineering, they generally compare mutants based on a single criteria (e.g., production rate at a mutant׳s maximum growth rate). As such, these approaches remain lim...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Metabolic Engineering Communications |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214030114000029 |