Optimization of Busulfan Dosing Regimen in Pediatric Patients Using a Population Pharmacokinetic Model Incorporating GST Mutations

Optimization of Busulfan Dosing Regimen in Pediatric Patients Using a Population Pharmacokinetic Model Incorporating GST Mutations

Jinjie Yuan,1,2 Ning Sun,1 Xinying Feng,3 Huan He,1 Dong Mei,1 Guanghua Zhu,4 Libo Zhao1 1Clinical Research Center, Beijing Children’s Hospital, Capital Medical University, Beijing, People’s Republic of China; 2School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical...

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Bibliographic Details
Main Authors: Yuan J, Sun N, Feng X, He H, Mei D, Zhu G, Zhao L
Format: Article
Language:English
Published: Dove Medical Press 2021-02-01
Series:Pharmacogenomics and Personalized Medicine
Subjects:
busulfan
gst polymorphisms
individualized therapy
population pharmacokinetics
hsct
Online Access:https://www.dovepress.com/optimization-of-busulfan-dosing-regimen-in-pediatric-patients-using-a--peer-reviewed-article-PGPM

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https://www.dovepress.com/optimization-of-busulfan-dosing-regimen-in-pediatric-patients-using-a--peer-reviewed-article-PGPM

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