Regulatory T Cell Responses to High-Dose Methylprednisolone in Active Systemic Lupus Erythematosus.

A slight increase in the proportion of circulating regulatory T (Treg) cells has been reported in systemic lupus erythematosus (SLE) patients taking oral prednisone. The effects of intravenous (IV) high dose methylprednisolone (MP) on Tregs have not yet been described, especially in active SLE.We pr...

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Main Authors: Alexis Mathian, Romain Jouenne, Driss Chader, Fleur Cohen-Aubart, Julien Haroche, Jehane Fadlallah, Laetitia Claër, Lucile Musset, Guy Gorochov, Zahir Amoura, Makoto Miyara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4667921?pdf=render