Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

Abstract Background Mast cells may activate fibroblasts and contribute to remodeling processes in the lung. However, the mechanism behind these actions needs to be further investigated. Fibroblasts are major regulators of on-going remodeling processes. Protease activated receptor 2 (PAR2) expressed...

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Bibliographic Details
Main Authors: Mariam Bagher, Anna-Karin Larsson-Callerfelt, Oskar Rosmark, Oskar Hallgren, Leif Bjermer, Gunilla Westergren-Thorsson
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cell Communication and Signaling
Subjects:
Human lung fibroblast
Lung
Mast cell
Migration
Protease activated receptor 2
Tryptase
Online Access:http://link.springer.com/article/10.1186/s12964-018-0269-3

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http://link.springer.com/article/10.1186/s12964-018-0269-3

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