Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins.

Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins.

BACKGROUND: Flavivirus infected cells produce infectious virions and subviral particles, both of which are formed by the assembly of prM and E envelope proteins and are believed to undergo the same maturation process. Dengue recombinant subviral particles have been produced in cell cultures with eit...

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Bibliographic Details
Main Authors: Pei-Gang Wang, Mateusz Kudelko, Joanne Lo, Lewis Yu Lam Siu, Kevin Tsz Hin Kwok, Martin Sachse, John M Nicholls, Roberto Bruzzone, Ralf M Altmeyer, Béatrice Nal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2790604?pdf=render

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http://europepmc.org/articles/PMC2790604?pdf=render

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