Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins.
BACKGROUND: Flavivirus infected cells produce infectious virions and subviral particles, both of which are formed by the assembly of prM and E envelope proteins and are believed to undergo the same maturation process. Dengue recombinant subviral particles have been produced in cell cultures with eit...
Main Authors: | Pei-Gang Wang, Mateusz Kudelko, Joanne Lo, Lewis Yu Lam Siu, Kevin Tsz Hin Kwok, Martin Sachse, John M Nicholls, Roberto Bruzzone, Ralf M Altmeyer, Béatrice Nal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2790604?pdf=render |
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