microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer

microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer

Abstract Background The aim of this study was to identify miRNAs specifically dysregulated in BRAF-mutated colorectal cancer, which could lead to a better understanding of the molecular mechanisms underlying oncogenesis of this malignant subtype of colorectal cancer. Methods Candidate dysregulated m...

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Bibliographic Details
Main Authors: Hidekazu Takahashi, Masanobu Takahashi, Shinobu Ohnuma, Michiaki Unno, Yuki Yoshino, Kota Ouchi, Shin Takahashi, Yasuhide Yamada, Hideki Shimodaira, Chikashi Ishioka
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Cancer
Subjects:
Colorectal cancer
BRAF
miRNA
miR-193a-3p
Anti-EGFR therapy
Online Access:http://link.springer.com/article/10.1186/s12885-017-3739-x

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http://link.springer.com/article/10.1186/s12885-017-3739-x

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