LDL apheresis as an alternate method for plasma LPS purification in healthy volunteers and dyslipidemic and septic patients

LDL apheresis as an alternate method for plasma LPS purification in healthy volunteers and dyslipidemic and septic patients

Lipopolysaccharide (LPS) is a key player for innate immunity activation. It is therefore a prime target for sepsis treatment, as antibiotics are not sufficient to improve outcome during septic shock. An extracorporeal removal method by polymyxin (PMX) B direct hemoperfusion (PMX-DHP) is used in Japa...

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Bibliographic Details
Main Authors: Auguste Dargent, Jean-Paul Pais de Barros, Samir Saheb, Randa Bittar, Wilfried Le Goff, Alain Carrié, Thomas Gautier, Isabelle Fournel, Anne Laure Rerole, Hélène Choubley, David Masson, Laurent Lagrost, Jean-Pierre Quenot
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Lipid Research
Subjects:
lipoproteins
low density lipoprotein
tandem mass spectroscopy
human and clinical research
inflammation
sepsis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520600359

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http://www.sciencedirect.com/science/article/pii/S0022227520600359

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