Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus.

Ebola virus (EBOV) causes severe and often fatal hemorrhagic fever in humans and nonhuman primates (NHPs). Currently, there are no licensed vaccines or therapeutics for human use. Recombinant vesicular stomatitis virus (rVSV)-based vaccine vectors, which encode an EBOV glycoprotein in place of the V...

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Bibliographic Details
Main Authors: Chad E Mire, Joan B Geisbert, Andrea Marzi, Krystle N Agans, Heinz Feldmann, Thomas W Geisbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3868506?pdf=render