Evaluation of the Antidepressant Activity, Hepatotoxicity and Blood Brain Barrier Permeability of Methyl Genipin

Geniposide (GE) is the main bioactive component of Gardeniae Fructus. The hepatotoxicity of geniposide limited clinical application. In order to get a new geniposide derivative that has less hepatotoxicity and still possesses the antidepressant activity, a new C-1 hydroxyl methylation derivative nam...

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Bibliographic Details
Main Authors: Xin Che, Meiyu Wang, Tian Wang, Huaying Fan, Mingyan Yang, Wenyan Wang, Hui Xu
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/7/923