Unique patterns of trimethylation of histone H3 lysine 4 are prone to changes during aging in Caenorhabditis elegans somatic cells.

Tri-methylation on histone H3 lysine 4 (H3K4me3) is associated with active gene expression but its regulatory role in transcriptional activation is unclear. Here we used Caenorhabditis elegans to investigate the connection between H3K4me3 and gene expression regulation during aging. We uncovered aro...

Full description

Bibliographic Details
Main Authors: Mintie Pu, Minghui Wang, Wenke Wang, Satheeja Santhi Velayudhan, Siu Sylvia Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6023244?pdf=render