Functions and Molecular Mechanisms of Deltex Family Ubiquitin E3 Ligases in Development and Disease

Functions and Molecular Mechanisms of Deltex Family Ubiquitin E3 Ligases in Development and Disease

Ubiquitination is a posttranslational modification of proteins that significantly affects protein stability and function. The specificity of substrate recognition is determined by ubiquitin E3 ligase during ubiquitination. Human Deltex (DTX) protein family, which functions as ubiquitin E3 ligases, c...

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Bibliographic Details
Main Authors: Lidong Wang, Xiaodan Sun, Jingni He, Zhen Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Deltex family proteins
ubiquitination
ubiquitin E3 ligase
ubiquitin code
protein homeostasis
post-translational modification
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.706997/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.706997/full

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