Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like Receptor 7

Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation via Toll-Like Receptor 7

The innate immune system senses influenza A virus (IAV) through different pathogen-recognition receptors including Toll-like receptor 7 (TLR7). Downstream of viral recognition natural killer (NK) cells are activated as part of the anti-IAV immune response. Despite the known decisive role of TLR7 for...

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Bibliographic Details
Main Authors: Sabine Stegemann-Koniszewski, Sarah Behrens, Julia D. Boehme, Inga Hochnadel, Peggy Riese, Carlos A. Guzmán, Andrea Kröger, Jens Schreiber, Matthias Gunzer, Dunja Bruder
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
influenza A virus
natural killer cells
pathogen-recognition receptors
Toll-like receptor 7
innate immunity
respiratory infection
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00245/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00245/full

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