Synthesis of 6-Nitroderivatives of Oxazolo[3,2-a]-pyridines and Their Reactions with Nucleophiles

5-Nitro-2-pyridone can be selectively N-phenacylated, and the resulting phenacylpyridones I undergo cyclization to 6-nitrooxazolo[3,2-a]pyridinium salts II. These salts II readily react with ammonia and aliphatic amines leading to the products of pyridine ring opening - previously unknown 1-amino-2-...

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Bibliographic Details
Main Authors: Eugene V. Babaev, Alexander A. Bush
Format: Article
Language:English
Published: MDPI AG 2003-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/8/6/460/