Pregnane X Receptor and Cancer: Context-Specificity is Key

Pregnane X Receptor and Cancer: Context-Specificity is Key

Pregnane X receptor (PXR) is an adopted orphan nuclear receptor that is activated by a wide-range of endobiotics and xenobiotics, including chemotherapy drugs. PXR plays a major role in the metabolism and clearance of xenobiotics and endobiotics in liver and intestine via induction of drug-metaboliz...

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Bibliographic Details
Main Authors: Satyanarayana R. Pondugula, Petr Pavek, Sridhar Mani
Format: Article
Language:English
Published: KenzPub 2016-06-01
Series:Nuclear Receptor Research
Subjects:
Pregnane X receptor
cancer
MDR
inflammation
nuclear receptor
Online Access:http://www.kenzpub.com/journals/nurr/2016/101198/

Internet

http://www.kenzpub.com/journals/nurr/2016/101198/

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