COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Precise genome editing using engineered nucleases can significantly facilitate biological studies and disease treatment. In particular, clustered regularly interspaced short palindromic repeats (CRISPR) with CRISPR-associated (Cas) proteins are a potentially powerful tool for modifying a genome by t...

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Bibliographic Details
Main Authors: Thomas J Cradick, Peng Qiu, Ciaran M Lee, Eli J Fine, Gang Bao
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
bioinformatics
bulges
off-target
program
RISPR
specificity
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116303523

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http://www.sciencedirect.com/science/article/pii/S2162253116303523

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