The effect of Deficient Muscarinic Signaling on Commonly Reported Biochemical Effects in Schizophrenia and Convergence with Genetic Susceptibility Loci in explaining symptom dimensions of psychosis.

With the advent of DSM 5 criticism has generally centred on a lack of biological validity of the diagnostic criteria. Part of the problem in describing a nosology of psychosis is the tacit assumption of multiple genetic causes each with an incremental loading on the clinical picture that fails to di...

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Bibliographic Details
Main Author: Costa eVakalopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00277/full