Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149
Abstract Background Hesperidin, a natural flavanone, has been proven to have multiple protective effects in diabetic rats, such as antioxidant, anti-inflammatory and anti-apoptotic effects. However, the molecular mechanisms underlying the effects of hesperidin are not well elucidated. Methods LO2 ce...
Main Authors: | Miao Tian, Yu-Bo Han, Cheng-Cheng Zhao, Li Liu, Fu-Li Zhang |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | Diabetology & Metabolic Syndrome |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13098-021-00664-1 |
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