Effects of Rare Microbiome Taxa Filtering on Statistical Analysis

Effects of Rare Microbiome Taxa Filtering on Statistical Analysis

Background: The accuracy of microbial community detection in 16S rRNA marker-gene and metagenomic studies suffers from contamination and sequencing errors that lead to either falsely identifying microbial taxa that were not in the sample or misclassifying the taxa of DNA fragment reads. Removing con...

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Bibliographic Details
Main Authors: Quy Cao, Xinxin Sun, Karun Rajesh, Naga Chalasani, Kayla Gelow, Barry Katz, Vijay H. Shah, Arun J. Sanyal, Ekaterina Smirnova
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Microbiology
Subjects:
filtering
fast permutation test
quality control
microbiome
contaminants
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.607325/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.607325/full

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