CTLA4 enhances the osteogenic differentiation of allogeneic human mesenchymal stem cells in a model of immune activation

Allogeneic mesenchymal stem cells (allo-MSCs) have recently garnered increasing interest for their broad clinical therapy applications. Despite this, many studies have shown that allo-MSCs are associated with a high rate of graft rejection unless immunosuppressive therapy is administered to control...

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Bibliographic Details
Main Authors: F. Dai, F. Zhang, D. Sun, Z.H. Zhang, S.W. Dong, J.Z. Xu
Format: Article
Published: Associação Brasileira de Divulgação Científica 2015-07-01
Series:Brazilian Journal of Medical and Biological Research
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000700629&lng=en&tlng=en