Genetic analysis of HA1 domain of influenza A/H3N2 viruses isolated in Kenya during the 2007–2013 seasons reveal significant divergence from WHO-recommended vaccine strains

Genetic analysis of HA1 domain of influenza A/H3N2 viruses isolated in Kenya during the 2007–2013 seasons reveal significant divergence from WHO-recommended vaccine strains

Background: Influenza viruses evolve rapidly and cause regular seasonal epidemics in humans challenging effective vaccination. The virus surface HA glycoprotein is the primary target for the host immune response. Here, we investigated the vaccine efficacy and evolution patterns of human influenza A/...

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Bibliographic Details
Main Authors: Edward M. Nyang’au, Wallace D. Bulimo, Victor Mobegi, Silvanos Opanda, Esther Magiri
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:International Journal of Infectious Diseases
Subjects:
A/H3N2
Antigenic site
Vaccine
Hemagglutinin
Kenya
P-epitope
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220302162

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http://www.sciencedirect.com/science/article/pii/S1201971220302162

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