Relationship between necrotic patterns in glioblastoma and patient survival: fractal dimension and lacunarity analyses using magnetic resonance imaging

Abstract Necrosis is a hallmark feature of glioblastoma (GBM). This study investigated the prognostic role of necrotic patterns in GBM using fractal dimension (FD) and lacunarity analyses of magnetic resonance imaging (MRI) data and evaluated the role of lacunarity in the biological processes leadin...

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Bibliographic Details
Main Authors: Shuai Liu, Yinyan Wang, Kaibin Xu, Zheng Wang, Xing Fan, Chuanbao Zhang, Shaowu Li, Xiaoguang Qiu, Tao Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08862-6