BRCA1 Expression Is Epigenetically Repressed in Sporadic Ovarian Cancer Cells by Overexpression of C-Terminal Binding Protein 2

BRCA1 Expression Is Epigenetically Repressed in Sporadic Ovarian Cancer Cells by Overexpression of C-Terminal Binding Protein 2

INTRODUCTION: Ovarian cancer is the leading cause of mortality from gynecological malignancy despite advancements in novel therapeutics. We have recently demonstrated that the transcriptional co-repressor C-terminal binding protein 2 (CtBP2) is overexpressed in epithelial ovarian carcinoma. MATERIA...

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Bibliographic Details
Main Authors: Taymaa May, Junzheng Yang, Melina Shoni, Shubai Liu, Housheng He, Reddy Gali, Shu-Kay Ng, Christopher Crum, Ross S. Berkowitz, Shu-Wing Ng
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613801339

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http://www.sciencedirect.com/science/article/pii/S1476558613801339

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